1=136LFTBDxHoHLFTBDxHoHLFTBDESESLFTBDoHESLFTBDESLFTBDoHLFTBDESESLFTBDoH442LFTBDLFTBDoHLFTBDESESLFTBDoHESLFTBDESLFTBDoHLFTBDESESLFTBDoH3LFTBDLFTBDoHLFTBDESESLFTBDoHESLFTBDESLFTBDoHLFTBDESESLFTBDoH4LFTBDLFTBDoHLFTBDESESES5LFTBDoHLFTBDoHLFTBDESESLFTBDoHESLFTBDESLFTBDoHLFTBDESESLFTBDoH6LFTBDLFTBDoHLFTBDESESLFTBDoHESLFTBDESLFTBDoHLFTBDESESLFTBDoH7LFTBDLFTBDoHLFTBDESESLFTBDoHESLFTBDESLFTBDoHLFTBDESESLFTBDoH8LFTBDESES0.18ES9Fig 1LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC210LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC211LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC212LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC213LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC214LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC215LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC216LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC217LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC218LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC219LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC220LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC221LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC222LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC223LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC224LFTBDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESESCC2Fin fig 1ES25Fig 2BDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC226LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC227LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC228LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESESCC2ES29LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC230LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC231LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC2let ring32LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDES1.04ESFin fig 2ESCC2ES33LFTBDxHLFTBDoHxHxHLFTBDoHxHxHLFTBDoHoHlet ringlet ring34LFTBDoHxHxHLFTBDoHxHxHLFTBDoHxHxHLFTBDoHoH35LFTBDoHxHxHLFTBDoHxHxHLFTBDoHxHxHLFTBDoHoHlet ring36LFTBDoHxHxHLFTBDoHxHxHLFTBDoHxHxHLFTBDoHoH37CC1CC2CC1CC2CC1CC2CC1CC238CC1CC2CC1CC2CC1CC2CC1CC239CC1CC2CC1CC2CC1CC2CC1CC240CC1CC2CC1CC2CC1CC2ESESESES41Fig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in fig 1ES57Fig 2BDLFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC258LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC259LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC260LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESESCC2ES61LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC262LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC263LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDESESLFTBDCC264LFTBDCC2LFTBDCC2LFTBDESESLFTBDCC2ESLFTBDESLFTBDCC2LFTBDES2.04ESFin fig 2ESCC2ES65BDLFTCC2BDLFTHFTBDLFTHFTHFTBDLFTHFTLT66BDLFTHFTBDLFTBDLFTHFTHFTBDLFTHFTAS67BDLFTBDLFTHFTBDLFTHFTHFTBDLFTHFTLT68BDLFTHFTBDLFTBDLFTHFTHFTBDLFTHFTAS69BDLFTBDLFTHFTBDLFTHFTHFTBDLFTHFTLT70BDLFTHFTBDLFTBDLFTHFTHFTBDLFTHFTAS71BDLFTBDLFTHFTBDLFTHFTHFTBDLFTHFTAS72BDLFTASBDLFTASBDLFTASBDLFTASAS73BDLFTCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC274BDLFTASCC2BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC175BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC276BDLFTASCC2BDLFTASCC2ASASASASASASASAS3377BDLFTCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC278BDLFTASCC2BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC179BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC280BDLFTfHfHASfHASfHBDLFTASfHfHfHfHBDLFTASfHASfHfHASfHBDLFTASfHLTfHLTfHLTfH81Fig 1BDLFTLTxHxHxHxHASxHxHxHxHBDLFTxHBDLFTxHxHBDLFTxHASxHxHBDLFToH82BDLFToHASxHxHxHxHBDLFTxHBDLFTxHxHBDLFTxHxHBDLFTxHASoH83BDLFTxHxHxHxHASxHxHxHxHBDLFTxHBDLFTxHxHBDLFTxHASxHxHBDLFToH84BDLFToHASxHxHxHxHBDLFTxHBDLFTxHxHBDLFTxHxHBDLFTxHASoH85BDLFTxHxHxHxHASxHxHxHxHBDLFTxHBDLFTxHxHBDLFTxHASxHxHBDLFToH86BDLFToHASxHxHxHxHBDLFTxHBDLFTxHxHBDLFTxHxHBDLFTxHASoH87BDLFTxHxHxHxHASxHxHxHxHBDLFTxHBDLFTxHxHBDLFTxHASxHxHBDLFToH88BDLFToHBDLFToHBDLFToHASFin fig 1ASLT89Fig 2BDLFTCC2BDLFTASBDLFTASBDLFTASBDLFT90ASBDLFTASBDLFTASBDLFTASBDLFT91MTLTLTASoHLTASoH92LTASoHLTAS93BDLFTCC2BDLFTASBDLFTASBDLFTASBDLFT94ASBDLFTASBDLFTASBDLFTASBDLFT95MTLTLTASoHLTASoH96LTASoHASASLTLTFin fig 2BDLFTLTBDLFTLT97BDLFTCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC298BDLFTASCC2BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC199BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC2100BDLFTASCC2ASCC2ASCC2ASCC2ASCC2ASCC2LT101BDLFTCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC2102BDLFTASCC2BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC1103BDLFTASCC2BDLFTASCC2BDLFTASCC2ASCC2BDLFTASCC2104BDLFTfHfHASfHASfHBDLFTASfHfHfHfHBDLFTASfHASfHfHASfHBDLFTASfHLTfHLTfHLTfH105BDLFTCC2xH106xHxH107xHxH108xHxH109xHxH110xHxH111xHxH112xHxHxHxH113HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs114HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs115HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs116HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs117HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs118HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs119HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs120HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs121HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs122HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs123HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs124HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs125HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs126HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs127HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs128HFTCsscscHFTCsscHFTASCsscHFTCsASscHFTCsASscHFTCsHFTASCsscHFTCs129ASASASASASASASASASASASASASASASASASASASAS130ASASASASASASASASASASASASLTASASASASASASAS131ASASASASASASASASASASASASASASASASASASASAS132ASASASASASASASASASASASASASASASASASASASAS133ASASASASASASASASASASASASASASASASASASASAS134ASASASASASASASASASASASASASASASASASASASAS135ASASASASASASASASASASASASASASASASASASASAS136ASASASASASASASSC137Fig 3HFTCC2CC1HFToHASWBoHWBHFToHHFTASWBoH138WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH139Fig 3HFTHFToHASWBoHWBHFToHHFTASWBoH140WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH141Fig 3HFTHFToHASWBoHWBHFToHHFTASWBoH142WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH143Fig 3HFTHFToHASWBoHWBHFToHHFTASWBoH144WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH145Fig 3HFTCC1CC2HFToHASWBoHWBHFToHHFTASWBoH146WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH147Fig 3HFTHFToHASWBoHWBHFToHHFTASWBoH148WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH149Fig 3HFTHFToHASWBoHWBHFToHHFTASWBoH150WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH151Fig 3HFTHFToHASWBoHWBHFToHHFTASWBoH152WBHFToHHFTASWBoHWBHFToHHFTASfig 3HFToH153HFTCC1CC2HFToHHFTASHFToHASHFTASHFToHHFTASHFToH154HFTHFToHHFTASHFToHASHFTASHFToHHFTASHFToH155HFTHFToHHFTASHFToHASHFTASHFToHHFTASHFToH156HFTHFToHHFTASHFToHASHFTASHFToHHFTASHFToH157HFTHFToHHFTASHFToHASHFTASHFToHHFTASHFToH158HFTHFToHHFTASHFToHASHFTASHFToHHFTASHFToH159HFTHFToHHFTASHFToHASHFTASHFToHHFTASHFToH160HFTHFToHHFTASHFTASASHFTASHFTASAS161